Everything about The D Arm totally explained
The
D arm is a feature in the
tertiary structure of
transfer RNA. It is comprised of the two D stems (four base pairs each each; 10-13 and 22-25) and the D loop. The D loop contains the base dihydrouracil. The D loop's main function is that of recognition. It is widely believed that it'll act as a recognition site for aminoacyl-tRNA synthetase which is an
enzyme involved in the aminoacylation of the
tRNA molecule. The D stem is also believed to have a recognition role although this is yet to be proved.
It is a highly variable region and is notable for its unusual conformation due to the over-crowding on one of the
guanosine residues. It appears to play a large role in the stabilization of the tRNA's
tertiary structure.
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